Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R011516 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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| Product Name | Anti-CDC25 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:3,000 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 98L88L09 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of human CDC25 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | GNRP; GRF1; CDC25; GRF55; CDC25L; H-GRF55; PP13187; ras-GRF1. |
|---|---|
| Molecular weight | Calculated MW: 145 kDa; Observed MW: 145 kDa |
| Uniprot ID | Q13972 |
| Gene ID | 5923 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-CDC25 Rabbit mAb [98L88L09] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009] |
|---|
| Cellular Location | Cytosol; growth cone; neuron projectionSource; plasma membrane. |
|---|
| Tissue Location | General cytoplasmic expression. |
|---|
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