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Anti-CDC25 Rabbit mAb [98L88L09]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R011516
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-CDC25 Rabbit mAb [98L88L09]
Product NameAnti-CDC25 Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:1,000~1:3,000
ReactivityRat
HostRabbit
ClonalityMonoclonal
Clone No.98L88L09
IsotypeIgG
LabelUnconjugated
ImmunogenRecombinant protein of human CDC25
FormatAffinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsGNRP; GRF1; CDC25; GRF55; CDC25L; H-GRF55; PP13187; ras-GRF1.
Molecular weightCalculated MW: 145 kDa; Observed MW: 145 kDa
Uniprot ID Q13972
Gene ID 5923
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-CDC25 Rabbit mAb [98L88L09] is for research use only and not for use in diagnostic or therapeutic procedures.
Background The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
Cellular Location Cytosol; growth cone; neuron projectionSource; plasma membrane.
Tissue Location General cytoplasmic expression.

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