Purified Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R011495 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-Lamin A/C Rabbit mAb [69M64L52]](https://files.epizyme.cn:5005/uploads/antybody/R011495_1.jpg)
![Anti-Lamin A/C Rabbit mAb [69M64L52]](https://files.epizyme.cn:5005/uploads/antybody/R011495_2.jpg)
![Anti-Lamin A/C Rabbit mAb [69M64L52]](https://files.epizyme.cn:5005/uploads/antybody/R011495_3.jpg)
![Anti-Lamin A/C Rabbit mAb [69M64L52]](https://files.epizyme.cn:5005/uploads/antybody/R011495_4.jpg)
| Product Name | Anti-Lamin A/C Rabbit mAb |
|---|---|
| Description | Purified Rabbit Monoclonal Antibody |
Application
|
ICC/IF (Cell), ELISA, WB, IHC-F/IF (Tissue-F), IHC-P/IF (Tissue-P) |
| Dilution | WB 1:500~1:1,000; IHC-P 1:50~1:100; IF 1:50~1:200 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 69M64L52 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic peptide of human Lamin A/C |
| Format | Buffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified. |
| Synonyms | LMNA, LMN1, Prelamin-A/C. |
|---|---|
| Molecular weight | Calculated MW: 74 kDa; Observed MW: 74,63 kDa |
| Uniprot ID | P02545 |
| Gene ID | 4000 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Lamin A/C antibody [69M64L52] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Play an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence. |
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