Purified Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R011384 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-PRAS40 Rabbit mAb [50L63L80]](https://files.epizyme.cn:5005/uploads/antybody/R011384_1.jpg)
| Product Name | Anti-PRAS40 Rabbit mAb |
|---|---|
| Description | Purified Rabbit Monoclonal Antibody |
Application
|
WB, IP, ELISA |
| Dilution | WB 1:500~1:1,000; IP 1:20 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 50L63L80 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic peptide of human PRAS40 |
| Format | Buffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified. |
| Synonyms | AKT1S1, PRAS40, Proline-rich AKT1 substrate 1, 40 kDa proline-rich AKT substrate. |
|---|---|
| Molecular weight | Calculated MW: 27 kDa; Observed MW: 40 kDa |
| Uniprot ID | Q96B36 |
| Gene ID | 84335 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-PRAS40 antibody [50L63L80] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | PRAS40 interacts with Raptor in mTOR complex 1 (mTORC1) in insulin-deprived cells and inhibits the activation of the mTORC1 pathway mediated by the cell cycle protein Rheb. Phosphorylation of PRAS40 by Akt at Thr246 relieves PRAS40 inhibition of mTORC1. mTORC1 in turn phosphorylates PRAS40 at Ser183. |
|---|
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