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Anti-14-3-3 theta Rabbit mAb [79K15K36]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R011209
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-14-3-3 theta Rabbit mAb [79K15K36]
Product NameAnti-14-3-3 theta Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:1,000~1:5,000
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.79K15K36
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human 14-3-3 Theta/Tau
FormatAffinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Synonyms14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1; YWHAQ.
Molecular weightCalculated MW: 28 kDa; Observed MW: 28 kDa
Uniprot ID P27348
Gene ID 10971
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-14-3-3 theta Rabbit mAb [79K15K36] is for research use only and not for use in diagnostic or therapeutic procedures.
Background This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
Cellular Location Cytoplasm.In neurons, axonally transported to the nerve terminals.
Tissue Location Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement.

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