Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R011198 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-ICAD Rabbit mAb [73K25M33]](https://files.epizyme.cn:5005/uploads/productimage/R011198-1.png)
| Product Name | Anti-ICAD Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:5,000 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 73K25M33 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human ICAD |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | A330085O09Rik, Caspase activated deoxyribonuclease inhibitor short form, DFF 1, DFF 45, DFF alpha, DFF-45, DFF1, DFF35, DFF45, DFFA, Dffa DNA fragmentation factor, alpha subunit, DFFA_HUMAN, DNA fragmentation factor 45 kDa subunit, DNA Fragmentation Factor Alpha Subunit, DNA fragmentation factor subunit alpha, DNA fragmentation factor, 45 kD, alpha subunit, DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1, DNA fragmentation factor, 45kDa, alpha polypeptide, DNA fragmentation factor, alpha subunit, DNAation factor 45 kDa subunit, H13, ICAD, ICAD L, ICAD S, Inhibitor of CAD, Inhibitor of Caspase Activated DNase, MGC143066, OTTHUMP00000001903, OTTHUMP00000001904, RP23 121D17.3. |
|---|---|
| Molecular weight | Calculated MW: 37 kDa; Observed MW: 45 kDa |
| Uniprot ID | O00273 |
| Gene ID | 1676 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-ICAD Rabbit mAb [73K25M33] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
|---|
| Cellular Location | Cytoplasm. |
|---|
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