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Anti-MEF2A Rabbit mAb [33K77L02]

Purified Rabbit Monoclonal Antibody

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货号 规格 价格
R011089
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-MEF2A Rabbit mAb [33K77L02]
Anti-MEF2A Rabbit mAb [33K77L02]
Product NameAnti-MEF2A Rabbit mAb
DescriptionPurified Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ICC/IF (Cell), ELISA
DilutionWB 1:500~1:1,000; IF 1:50~1:200
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.33K77L02
IsotypeIgG
LabelUnconjugated
ImmunogenA synthetic peptide of human MEF2A
FormatBuffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified.
Synonymsmef2, ADCAD1, RSRFC4, RSRFC9.
Molecular weightCalculated MW: 55 kDa; Observed MW: 55 kDa
Uniprot ID Q02078
Gene ID 4205
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-MEF2A antibody [33K77L02] is for research use only and not for use in diagnostic or therapeutic procedures.
Background Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.

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