Purified Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R010836 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-Rad51D Rabbit mAb [28K88L54]](https://files.epizyme.cn:5005/uploads/antybody/R010836_1.jpg)
| Product Name | Anti-Rad51D Rabbit mAb |
|---|---|
| Description | Purified Rabbit Monoclonal Antibody |
Application
|
WB, IP, ELISA |
| Dilution | WB 1:500~1:1,000; IP 1:20 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 28K88L54 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of human Rad51D |
| Format | Buffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified. |
| Synonyms | TRAD, R51H3, BROVCA4, RAD51L3. |
|---|---|
| Molecular weight | Calculated MW: 35 kDa; Observed MW: 35 kDa |
| Uniprot ID | O75771 |
| Gene ID | 5892 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Rad51D antibody [28K88L54] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM. |
|---|
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