Purified Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R010738 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-PKN1 Rabbit mAb [98L59L98]](https://files.epizyme.cn:5005/uploads/antybody/R010738_1.jpg)
| Product Name | Anti-PKN1 Rabbit mAb |
|---|---|
| Description | Purified Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:500~1:1,000 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 98L59L98 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic peptide of human PKN |
| Format | Buffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified. |
| Synonyms | DBK, PKN, PAK1, PRK1, PAK-1, PRKCL1, PKN-ALPHA. |
|---|---|
| Molecular weight | Calculated MW: 104 kDa; Observed MW: 120 kDa |
| Uniprot ID | Q16512 |
| Gene ID | 5585 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-PKN1 antibody [98L59L98] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
|---|
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