Purified Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R010482 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-DAPK2 Rabbit mAb [41M10M58]](https://files.epizyme.cn:5005/uploads/antybody/R010482_1.jpg)
| Product Name | Anti-DAPK2 Rabbit mAb |
|---|---|
| Description | Purified Rabbit Monoclonal Antibody |
Application
|
WB, IHC-P/IF (Tissue-P), ELISA |
| Dilution | WB 1:500~1:1,000; IHC-P 1:50~1:100 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 41M10M58 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic peptide of human DAPK2 |
| Format | Buffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified. |
| Synonyms | DAPK2, Death-associated protein kinase 2, DAP kinase 2, DAP-kinase-related protein 1, DRP-1. |
|---|---|
| Molecular weight | Calculated MW: 43 kDa; Observed MW: 43 kDa |
| Uniprot ID | Q9UIK4 |
| Gene ID | 23604 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-DAPK2 antibody [41M10M58] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (PubMed:17347302). Regulates granulocytic motility by controlling cell spreading and polarization (PubMed:24163421). |
|---|
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