Purified Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R010439 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-NOLC1 Rabbit mAb [90K32L53]](https://files.epizyme.cn:5005/uploads/antybody/R010439_1.jpg)
![Anti-NOLC1 Rabbit mAb [90K32L53]](https://files.epizyme.cn:5005/uploads/antybody/R010439_2.jpg)
![Anti-NOLC1 Rabbit mAb [90K32L53]](https://files.epizyme.cn:5005/uploads/antybody/R010439_3.jpg)
| Product Name | Anti-NOLC1 Rabbit mAb |
|---|---|
| Description | Purified Rabbit Monoclonal Antibody |
Application
|
WB, IHC-F/IF (Tissue-F), IHC-P/IF (Tissue-P), ICC/IF (Cell), ELISA |
| Dilution | WB 1:500~1:1,000; IHC-P 1:50~1:100; IF 1:50~1:200 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 90K32L53 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic peptide of human NOLC1 |
| Format | Buffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified. |
| Synonyms | P130, NOPP130, NOPP140, NS5ATP13. |
|---|---|
| Molecular weight | Calculated MW: 74 kDa; Observed MW: 110 kDa |
| Uniprot ID | Q14978 |
| Gene ID | 9221 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-NOLC1 antibody [90K32L53] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification (PubMed:10567578, PubMed:26399832). Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832). Involved in nucleologenesis, possibly by playing a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus (PubMed:9016786). It has intrinsic GTPase and ATPase activities (PubMed:9016786). |
|---|
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