Purified Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R010422 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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| Product Name | Anti-Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) Rabbit mAb |
|---|---|
| Description | Purified Rabbit Monoclonal Antibody |
Application
|
WB, IHC-P/IF (Tissue-P), ELISA |
| Dilution | WB 1:500~1:1,000; IHC-P 1:50~1:100 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 46L73M48 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser181 of human TAOK1 |
| Format | Buffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified. |
| Synonyms | DPK, JIK, hKFC-A, MAP3K18. |
|---|---|
| Molecular weight | Calculated MW: 116 kDa; Observed MW: 105,116,138 kDa |
| Uniprot ID | Q7L7X3 , Q9H2K8 , Q9UL54 |
| Gene ID | 51347 , 57551 , 9344 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) antibody [46L73M48] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. |
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