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Anti-Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) Rabbit mAb [46L73M48]

Purified Rabbit Monoclonal Antibody

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货号 规格 价格
R010422
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) Rabbit mAb [46L73M48]
Anti-Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) Rabbit mAb [46L73M48]
Anti-Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) Rabbit mAb [46L73M48]
Product NameAnti-Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) Rabbit mAb
DescriptionPurified Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P/IF (Tissue-P), ELISA
DilutionWB 1:500~1:1,000; IHC-P 1:50~1:100
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.46L73M48
IsotypeIgG
LabelUnconjugated
ImmunogenA synthetic phosphopeptide corresponding to residues surrounding Ser181 of human TAOK1
FormatBuffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified.
SynonymsDPK, JIK, hKFC-A, MAP3K18.
Molecular weightCalculated MW: 116 kDa; Observed MW: 105,116,138 kDa
Uniprot ID Q7L7X3 , Q9H2K8 , Q9UL54
Gene ID 51347 , 57551 , 9344
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) antibody [46L73M48] is for research use only and not for use in diagnostic or therapeutic procedures.
Background Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6.

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