Purified Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R010250 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-Bak Rabbit mAb [94K40K04]](https://files.epizyme.cn:5005/uploads/antybody/R010250_1.jpg)
![Anti-Bak Rabbit mAb [94K40K04]](https://files.epizyme.cn:5005/uploads/antybody/R010250_2.jpg)
| Product Name | Anti-Bak Rabbit mAb |
|---|---|
| Description | Purified Rabbit Monoclonal Antibody |
Application
|
WB, IHC-P/IF (Tissue-P), IP, ELISA |
| Dilution | WB 1:500~1:1,000; IHC-P 1:50~1:100; IP 1:20 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 94K40K04 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic peptide of human Bak |
| Format | Buffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified. |
| Synonyms | BAK1, BAK, BCL2L7, CDN1, Bcl-2 homologous antagonist/killer, Apoptosis regulator BAK, Bcl-2-like protein 7, Bcl2-L-7. |
|---|---|
| Molecular weight | Calculated MW: 23 kDa; Observed MW: 23 kDa |
| Uniprot ID | Q16611 |
| Gene ID | 578 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Bak antibody [94K40K04] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Bak is a proapoptotic member of the Bcl-2 family. This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway. Upon apoptotic stimulation, an upstream stimulator like truncated BID (tBID) induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase-9 pathway and eventually leads to cell death. |
|---|
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