Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R010112 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-CDC42 Rabbit mAb [11L56M54]](https://files.epizyme.cn:5005/uploads/products/202511/R010112-1.png)
![Anti-CDC42 Rabbit mAb [11L56M54]](https://files.epizyme.cn:5005/uploads/products/202511/R010112-2.png)
| Product Name | Anti-CDC42 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, IHC-P/IF (Tissue-P), ELISA |
| Dilution | WB 1:1,000~1:5,000; IHC-P 1:100~1:200; IF 1:100~1:200 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 11L56M54 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of human CDC42 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | Cell division control protein 42 homolog; G25K GTP-binding protein; CDC42. |
|---|---|
| Molecular weight | Calculated MW: 21 kDa; Observed MW: 21 kDa |
| Uniprot ID | P60953 |
| Gene ID | 998 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-CDC42 Rabbit mAb [11L56M54] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
|---|
| Cellular Location | Cell membrane.Lipid-anchor.Cytoplasmic side.Cytoplasm.Cytoskeleton.Microtubule organizing center.Centrosome.Cytoplasm.Cytoskeleton.Spindle.Midbody.Cell projection.Dendrite.Localizes to spindle during prometaphase cells. Moves to the central spindle as cells progressed through anaphase to telophase (PubMed:15642749). Localizes at the end of cytokinesis in the intercellular bridge formed between two daughter cells (PubMed:15642749). Its localization is regulated by the activities of guanine nucleotide exchange factor ECT2 and GTPase activating protein RACGAP1 (PubMed:15642749). Colocalizes with NEK6 in the centrosome (PubMed:20873783). In its active GTP-bound form localizes to the leading edge membrane of migrating dendritic cells (By similarity). |
|---|
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