Purified Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R010064 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-Bax Rabbit mAb [42M91M87]](https://files.epizyme.cn:5005/uploads/antybody/R010064_1.jpg)
| Product Name | Anti-Bax Rabbit mAb |
|---|---|
| Description | Purified Rabbit Monoclonal Antibody |
Application
|
IP, ELISA, WB |
| Dilution | WB 1:500~1:1,000; IP 1:20 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 42M91M87 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic peptide of human Bax |
| Format | Buffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified. |
| Synonyms | Apoptosis regulator BAX, BAX, Bcl-2-like protein 4, BCL2-associated X protein, Bcl2-L-4, BCL2L4. |
|---|---|
| Molecular weight | Calculated MW: 21 kDa; Observed MW: 21 kDa |
| Uniprot ID | Q07812 |
| Gene ID | 581 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Bax antibody [42M91M87] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis. |
|---|
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