Affinity Purified Rabbit Polyclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| P900002 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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| Product Name | Anti-ATP5A1 Rabbit pAb |
|---|---|
| Description | Affinity Purified Rabbit Polyclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | This ATP5A1 antibody is generated from rabbits immunized with a BSA conjugated synthetic peptide between 99-113 amino acids from the N-terminal region of human ATP5A1. |
| Format | Purified polyclonal antibody supplied in PBS with 0.01% (W/V) sodium azide and 50% glycerol, pH 7.3. This antibody is purified through a protein G column. |
| Synonyms | ATP synthase subunit alpha, mitochondrial, ATP5A1, ATP5A, ATP5AL2, ATPM, ATP5F1A, ATP5AL2, ATPM, hATP1, OMR, ORM. |
|---|---|
| Calculated MW | Calculated MW: 60 kDa; Observed MW: 52 kDa |
| Primary Accession | P25705 |
| Other Accession | NP_001001937.1; P15999; Q03265; P19483 |
| Gene ID | 498 |
| Antigen Region | 99-113aa |
| Storage | Shipped on wet ice. Store at 20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-ATP5A1 Rabbit pAb is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a subunit of mitochondrial ATP synthase.Mitochondrial membrane ATP synthase (F1F0?ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F1. Rotation of the central stalk against the surrounding alpha3beta3 subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity).Binds the bacterial siderophore enterobactin and can promote mitochondrial accumulation of enterobactin-derived iron ions |
|---|
| Cellular Location | Mitochondrion. Mitochondrion inner membrane {ECO:0000250|UniProtKB:P19483}; Peripheral membrane protein {ECO:0000250|UniProtKB:P19483}; Matrix side {ECO:0000250|UniProtKB:P19483}. Cell membrane; Peripheral membrane protein; Extracellular side. Note=Colocalizes with HRG on the cell surface of T-cells. |
|---|
| Tissue Location | Fetal lung, heart, liver, gut and kidney. Expressed at higher levels in the fetal brain, retina and spinal cord. |
|---|
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