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Anti-Phospho-FAK (Tyr576/Tyr577) Rabbit pAb

Purified Rabbit Polyclonal Antibody

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货号 规格 价格
P108735
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-Phospho-FAK (Tyr576/Tyr577) Rabbit pAb
Product NameAnti-Phospho-FAK (Tyr576/Tyr577) Rabbit pAb
DescriptionPurified Rabbit Polyclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:500~1:2,000
ReactivityHuman
HostRabbit
ClonalityPolyclonal
IsotypeIgG
LabelUnconjugated
ImmunogenA synthetic phosphorylated peptide around Y576 & Y577 of human PTK2 (NP_722560.1).
FormatAffinity purified polyclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsFAK; FADK; FAK1; FRNK; FADK 1; PPP1R71; p125FAK; pp125FAK; Phospho-FAK-Y576/577.
Molecular weightCalculated MW: 119 kDa; Observed MW: 130 kDa
Uniprot ID Q05397
Gene ID 5747
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-Phospho-FAK (Tyr576/Tyr577) Rabbit pAb is for research use only and not for use in diagnostic or therapeutic procedures.
Background This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.

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