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Anti-RNF7 Rabbit pAb

Purified Rabbit Polyclonal Antibody

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货号 规格 价格
P106835
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-RNF7 Rabbit pAb
Product NameAnti-RNF7 Rabbit pAb
DescriptionPurified Rabbit Polyclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF (Cell)/ICC, ELISA
DilutionWB 1:500~1:2,000; IF 1:20~1:50
ReactivityHuman
HostRabbit
ClonalityPolyclonal
IsotypeIgG
LabelUnconjugated
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human RNF7 (NP_055060.1).
FormatAffinity purified polyclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsSAG; ROC2; rbx2; CKBBP1; RNF7.
Molecular weightCalculated MW: 13 kDa; Observed MW: Refer to figures
Uniprot ID Q9UBF6
Gene ID 9616
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-RNF7 Rabbit pAb is for research use only and not for use in diagnostic or therapeutic procedures.
Background The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.

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