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Anti-Methionine Aminopeptidase 2 Rabbit pAb

Purified Rabbit Polyclonal Antibody

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货号 规格 价格
P106618
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-Methionine Aminopeptidase 2 Rabbit pAb
Product NameAnti-Methionine Aminopeptidase 2 Rabbit pAb
DescriptionPurified Rabbit Polyclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:200~1:2,000
ReactivityHuman, Mouse
HostRabbit
ClonalityPolyclonal
IsotypeIgG
LabelUnconjugated
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human METAP2 (NP_006829.1).
FormatAffinity purified polyclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsMAP2; MNPEP; p67eIF2; METAP2.
Molecular weightCalculated MW: 53 kDa; Observed MW: 60 kDa
Uniprot ID P50579
Gene ID 10988
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-Methionine Aminopeptidase 2 Rabbit pAb is for research use only and not for use in diagnostic or therapeutic procedures.
Background The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.

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