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Anti-SKP1 Rabbit pAb

Purified Rabbit Polyclonal Antibody

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货号 规格 价格
P105492
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-SKP1 Rabbit pAb
Anti-SKP1 Rabbit pAb
Anti-SKP1 Rabbit pAb
Product NameAnti-SKP1 Rabbit pAb
DescriptionPurified Rabbit Polyclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:500~1:2,000
ReactivityHuman, Mouse
HostRabbit
ClonalityPolyclonal
IsotypeIgG
LabelUnconjugated
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-163 of human SKP1 (NP_733779.1).
FormatAffinity purified polyclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsOCP2; p19A; EMC19; SKP1A; OCP-II; TCEB1L; SKP1.
Molecular weightCalculated MW: 19 kDa; Observed MW: 19 kDa
Uniprot ID P63208
Gene ID 6500
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-SKP1 Rabbit pAb is for research use only and not for use in diagnostic or therapeutic procedures.
Background This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

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