Purified Rabbit Polyclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| P105160 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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| Product Name | Anti-PCSK9 Rabbit pAb |
|---|---|
| Description | Purified Rabbit Polyclonal Antibody |
Application
|
WB, IF (Cell)/ICC, IP, ELISA |
| Dilution | WB 1:500~1:1,000; IF 1:50~1:200; IP 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 31-692 of human PCSK9 (NP_777596.2). |
| Format | Affinity purified polyclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | PCSK9; FH3; HCHOLA3; LDLCQ1; NARC-1; FHCL3; NARC1; PC9; proprotein convertase subtilisin/kexin type 9; Proprotein Convertase 9(PCSK9). |
|---|---|
| Molecular weight | Calculated MW: 20 kDa/74 kDa; Observed MW: 65 kDa/80 kDa/65 kDa,80 kDa |
| Uniprot ID | Q8NBP7 |
| Gene ID | 255738 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-PCSK9 Rabbit pAb is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. |
|---|
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