Purified Rabbit Polyclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| P105135 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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| Product Name | Anti-SQSTM1 Rabbit pAb |
|---|---|
| Description | Purified Rabbit Polyclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:500~1:2,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 250-350 of mouse SQSTM1 (NP_035148.1). |
| Format | Affinity purified polyclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | Osi; p62; A170; STAP; OSF-6; STONE14; SQSTM1. |
|---|---|
| Molecular weight | Calculated MW: 48 kDa; Observed MW: 62 kDa |
| Uniprot ID | Q64337 |
| Gene ID | 18412 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-SQSTM1 Rabbit pAb is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Enables K63-linked polyubiquitin modification-dependent protein binding activity; identical protein binding activity; and ionotropic glutamate receptor binding activity. Involved in several processes, including brown fat cell proliferation; energy homeostasis; and positive regulation of long-term synaptic potentiation. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in several cellular components, including aggresome; autolysosome; and sperm midpiece. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study Paget's disease of bone. Human ortholog(s) of this gene implicated in GNE myopathy; Paget's disease of bone; and frontotemporal dementia and/or amyotrophic lateral sclerosis-3. Orthologous to human SQSTM1 (sequestosome 1). |
|---|
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