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Anti-4E-BP1 Rabbit pAb

Purified Rabbit Polyclonal Antibody

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货号 规格 价格
P103594
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-4E-BP1 Rabbit pAb
Product NameAnti-4E-BP1 Rabbit pAb
DescriptionPurified Rabbit Polyclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P/IF (Tissue-P), ELISA
DilutionIHC-P 1:50~1:200
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityPolyclonal
IsotypeIgG
LabelUnconjugated
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human eIF4EBP1 (NP_004086.1).
FormatAffinity purified polyclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsBP-1; 4EBP1; 4E-BP1; PHAS-I; eIF4EBP1.
Molecular weightCalculated MW: 13 kDa
Uniprot ID Q13541
Gene ID 1978
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-4E-BP1 Rabbit pAb is for research use only and not for use in diagnostic or therapeutic procedures.
Background This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

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