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Anti-NLRP10 Rabbit pAb

Purified Rabbit Polyclonal Antibody

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货号 规格 价格
P102829
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-NLRP10 Rabbit pAb
Product NameAnti-NLRP10 Rabbit pAb
DescriptionPurified Rabbit Polyclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:500~1:2,000
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityPolyclonal
IsotypeIgG
LabelUnconjugated
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NLRP10 (NP_789791.1).
FormatAffinity purified polyclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsNOD8; PAN5; PYNOD; NALP10; CLR11.1; NLRP10.
Molecular weightCalculated MW: 75 kDa; Observed MW: 75 kDa
Uniprot ID Q86W26
Gene ID 338322
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-NLRP10 Rabbit pAb is for research use only and not for use in diagnostic or therapeutic procedures.
Background Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.

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