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Anti-CISH Rabbit pAb

Purified Rabbit Polyclonal Antibody

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货号 规格 价格
P102421
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-CISH Rabbit pAb
Anti-CISH Rabbit pAb
Product NameAnti-CISH Rabbit pAb
DescriptionPurified Rabbit Polyclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF (Cell)/ICC, ELISA
DilutionWB 1:1,000~1:5,000; IF 1:50~1:200
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityPolyclonal
IsotypeIgG
LabelUnconjugated
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 17-130 of human CISH (NP_659508.1).
FormatAffinity purified polyclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsCIS; G18; SOCS; CIS-1; BACTS2; CISH.
Molecular weightCalculated MW: 29 kDa; Observed MW: 37 kDa
Uniprot ID Q9NSE2
Gene ID 1154
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-CISH Rabbit pAb is for research use only and not for use in diagnostic or therapeutic procedures.
Background The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

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