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Anti-SOCS3 Rabbit pAb

Purified Rabbit Polyclonal Antibody

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货号 规格 价格
P100248
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-SOCS3 Rabbit pAb
Anti-SOCS3 Rabbit pAb
Anti-SOCS3 Rabbit pAb
Anti-SOCS3 Rabbit pAb
Product NameAnti-SOCS3 Rabbit pAb
DescriptionPurified Rabbit Polyclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF (Cell)/ICC, ELISA
DilutionWB 1:500~1:1,000; IF 1:50~1:200
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityPolyclonal
IsotypeIgG
LabelUnconjugated
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 101-225 of human SOCS3 (NP_003946.3).
FormatAffinity purified polyclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsCIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3; SOCS3.
Molecular weightCalculated MW: 25 kDa; Observed MW: 26 kDa/25 kDa
Uniprot ID O14543
Gene ID 9021
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-SOCS3 Rabbit pAb is for research use only and not for use in diagnostic or therapeutic procedures.
Background This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

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