Purified Rabbit Polyclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| P100174 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
| Product Name | Anti-CD45 Rabbit pAb |
|---|---|
| Description | Purified Rabbit Polyclonal Antibody |
Application
|
WB, IF (Cell)/ICC, IP, ELISA |
| Dilution | WB 1:500~1:1,000; IF 1:50~1:200; IP 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 611-730 of human CD45 (NP_002829.3). |
| Format | Affinity purified polyclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105. |
|---|---|
| Molecular weight | Calculated MW: 147 kDa; Observed MW: 200-250 kDa |
| Uniprot ID | P08575 |
| Gene ID | 5788 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-CD45 Rabbit pAb is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. |
|---|
总篇数：加载中...
总影响因子：加载中...
最高影响因子：加载中...
上海市闵行区新骏环路760号1号楼3层
400-058-8030
技术支持(电话/微信)：
罗老师 15021027255
李老师 18301721288
黄老师 18217238522
如有任何关于雅酶产品问题
欢迎来信咨询
雅酶微信公众号
Copyright © 2026上海雅酶生物医药科技有限公司（Epizyme Biotech）
沪ICP备2021002422号
