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[KO Validated] Anti-ERK2 Rabbit pAb

Purified Rabbit Polyclonal Antibody

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货号 规格 价格
P100079
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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[KO Validated] Anti-ERK2 Rabbit pAb
[KO Validated] Anti-ERK2 Rabbit pAb
Product Name[KO Validated] Anti-ERK2 Rabbit pAb
DescriptionPurified Rabbit Polyclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF (Cell)/ICC, ELISA
DilutionWB 1:500~1:1,000; IF 1:50~1:200
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityPolyclonal
IsotypeIgG
LabelUnconjugated
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 200-300 of human ERK2 (NP_002736.3).
FormatAffinity purified polyclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsERK; p38; p40; p41; ERK2; ERT1; NS13; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK; ERK2.
Molecular weightCalculated MW: 41 kDa; Observed MW: 42 kDa
Uniprot ID P28482
Gene ID 5594
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-ERK2 Rabbit pAb is for research use only and not for use in diagnostic or therapeutic procedures.
Background This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

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