Purified Rabbit Polyclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| P059375 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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| Product Name | Anti-Phospho-MYPT1 (Thr696) Rabbit pAb |
|---|---|
| Description | Purified Rabbit Polyclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:500 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | This Phospho-MYPT1 (Thr696) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 669-702 amino acids from human MYPT1. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Synonyms | Protein phosphatase 1 regulatory subunit 12A, Myosin phosphatase-targeting subunit 1, Myosin phosphatase target subunit 1, Protein phosphatase myosin-binding subunit, PPP1R12A, MBS, MYPT1. |
|---|---|
| Calculated MW | 115 kDa |
| Uniprot ID | O14974 |
| Other Accession | Q90623; Q6DRG7; Q9DBR7; Q10728 |
| Gene ID | 4659 |
| Storage | Shipped on wet ice. Store at 20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Phospho-MYPT1 (Thr696) antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity. |
|---|
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton, stress fiber. Note=Also along actomyosin filaments. |
|---|
| Tissue Location | Expressed in striated muscles, specifically in type 2a fibers (at protein level). |
|---|
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