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Anti-ATP Citrate lyase Rabbit pAb

Purified Rabbit Polyclonal Antibody

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货号 规格 价格
P011395
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-ATP Citrate lyase Rabbit pAb
Anti-ATP Citrate lyase Rabbit pAb
Product NameAnti-ATP Citrate lyase Rabbit pAb
DescriptionPurified Rabbit Polyclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P/IF (Tissue-P), ICC/IF (Cell), IP, FC, ELISA, WB
DilutionWB 1:500~1:1,000; IHC-P 1:50~1:100; IF 1:50~1:200; IP 1:20; FC 1:50~1:100
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityPolyclonal
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human ATP citrate lyase
FormatBuffer System: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Purification: Affinity Chromatography
SynonymsACLY, ATP-citrate synthase, ATP-citrate, pro-S-)-lyase, ACL, Citrate cleavage enzyme.
Molecular weightCalculated MW: 121 kDa; Observed MW: 121 kDa
Uniprot ID P53396
Gene ID 47
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-ATP Citrate lyase antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Background ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.

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