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Anti-Cofilin Rabbit pAb

Purified Rabbit Polyclonal Antibody

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货号 规格 价格
P011284
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-Cofilin Rabbit pAb
Anti-Cofilin Rabbit pAb
Anti-Cofilin Rabbit pAb
Product NameAnti-Cofilin Rabbit pAb
DescriptionPurified Rabbit Polyclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P/IF (Tissue-P), ICC/IF (Cell), ELISA
DilutionWB 1:500~1:1,000; IHC-P 1:50~1:100; IF 1:50~1:200
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityPolyclonal
IsotypeIgG
LabelUnconjugated
ImmunogenPeptide sequence around derived from Human coflin1/cofilin2.
FormatBuffer System: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Purification: Affinity Chromatography
SynonymsCFL1, CFL, Cofilin-1, 18 kDa phosphoprotein, p18, Cofilin, non-muscle isoform.
Molecular weightCalculated MW: 19 kDa; Observed MW: 19 kDa
Uniprot ID P23528
Gene ID 1072
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-Cofilin antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Background The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]

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