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Anti-SQSTM1/p62 Rabbit pAb

Purified Rabbit Polyclonal Antibody

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货号 规格 价格
P010823
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-SQSTM1/p62 Rabbit pAb
Anti-SQSTM1/p62 Rabbit pAb
Product NameAnti-SQSTM1/p62 Rabbit pAb
DescriptionPurified Rabbit Polyclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
ELISA, WB, ICC/IF (Cell), FC
DilutionWB 1:500~1:1,000; IF 1:50~1:200; FC 1:50~1:100
ReactivityRat, Human, Mouse
HostRabbit
ClonalityPolyclonal
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human p62/SQSTM1
FormatBuffer System: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Purification: Affinity Chromatography
Synonymsp60, p62, A170, DMRV, OSIL, PDB3, ZIP3, p62B, NADGP, FTDALS3.
Molecular weightCalculated MW: 48 kDa; Observed MW: 62 kDa
Uniprot ID Q13501
Gene ID 8878
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-SQSTM1/p62 antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Background Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1.

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