Purified Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M900041 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-Caspase 7 Mouse mAb [57G70D02]](https://cdn.epizyme.cn/uploads/products/202602/M900041-1.png?v=20260226165827)
![Anti-Caspase 7 Mouse mAb [57G70D02]](https://cdn.epizyme.cn/uploads/products/202602/M900041-2.png?v=20260226165827)
| Product Name | Anti-Caspase 7 Mouse mAb |
|---|---|
| Description | Purified Recombinant Mouse Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 57G70D02 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of human Caspase 7 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | MCH3; CASP7; Caspase-7; CASP-7; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3. |
|---|---|
| Molecular weight | Calculated MW: 34 kDa; Observed MW: 37 kDa |
| Uniprot ID | P55210 |
| Gene ID | 840 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Caspase 7 Mouse mAb [57G70D02] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012] |
|---|
| Cellular Location | Cytoplasm, cytosol Nucleus Secreted, extracellular space Note: Following cleavage and activation by CASP1 or granzyme B (GZMB), secreted into the extracellular milieu by passing through the gasdermin-D (GSDMD) pores or perforin (PRF1) pore, respectively. |
|---|
| Tissue Location | Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain. |
|---|
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