Purified Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M020020 | ||
| 20µL | ¥738.00 | |
| 50µL | ¥1380.00 | |
| 100µL | ¥2280.00 |
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![[KD Validated] Anti-ADGRG1 Mouse mAb [91D53G90]](https://cdn.epizyme.cn/uploads/products/202604/M020020-WB-KD-1.png?v=20260420170219)
![[KD Validated] Anti-ADGRG1 Mouse mAb [91D53G90]](https://cdn.epizyme.cn/uploads/products/202604/M020020-WB-1.png?v=20260420170219)
| Product Name | [KD Validated] Anti-ADGRG1 Mouse mAb |
|---|---|
| Description | Purified Recombinant Mouse Monoclonal Antibody |
Application
|
WB |
| Dilution | WB 1:500~1:2,500 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 91D53G90 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of human GPR56 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | ADGRG1; Adhesion G Protein-Coupled Receptor G1; TM7LN4; TM7XN1; GPR56; Adhesion G-Protein Coupled Receptor G1; G Protein-Coupled Receptor 56; 7-Transmembrane Protein With No EGF-Like N-Terminal Domains-1; Testicular Tissue Protein Li 77; G-Protein Coupled Receptor 56; CDCBM14B; CDCBM15A; BFPP; BPPR. |
|---|---|
| Molecular weight | Calculated MW: 78 kDa; Observed MW: 55-70 kDa |
| Uniprot ID | Q9Y653 |
| Gene ID | 9289 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 12 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | [KD Validated] Anti-ADGRG1 Mouse mAb [91D53G90] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
|---|
| Cellular Location | Cell membrane Multi-pass membrane protein ADGRG1 N-terminal fragment Secreted ADGRG1 C-terminal fragment Membrane raft Interaction with its ligand COL3A1 leads to the release of ADGRG1 NT from the membrane and triggers the association of ADGRG1 CT with lipid rafts. |
|---|
| Tissue Location | Widely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells. Expression is down-regulated in different tumors from highly metastatic cells. |
|---|
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