Anti-Caspase 1 Mouse mAb [88J80A65]

抗体系列

Anti-Caspase 1 Mouse mAb [88J80A65]

Purified Recombinant Mouse Monoclonal Antibody

一键复制产品信息

货号	规格	价格
M016264
	20µL	¥588.00
	50µL	¥1080.00
	100µL	¥1780.00

立即购买

Western Blot - Anti-Caspase 1 Mouse mAb [88J80A65]

All lanes: M016264 at 1:1,000 dilution

Lane 1: HeLa (Human cervix adenocarcinoma epithelial cell) whole cell lysates

Lane 2: HepG2 (Human hepatocarcinoma epithelial cell) whole cell lysates

Lane 3: HCT116 (Human colorectal carcinoma epithelial cell) whole cell lysates

Lane 4: MCF-7 (Human breast adenocarcinoma epithelial cell) whole cell lysates

Lane 5: 293T (Human embryonic kidney cell) whole cell lysates

Lane 6: Raw264.7 (Mouse mononuclear macrophage leukemia cell) whole cell lysates

Lane 7: Mouse skin whole tissue lysates

Lane 8: Mouse muscle whole tissue lysates

Lane 9: PC-12 (Rat adrenal pheochromocytoma epithelial cell) whole cell lysates

Lane 10: Rat skin whole tissue lysates

Secondary antibody: Goat Anti-Mouse IgG (H+L), HRP Conjugated (Cat. No. LF101) at 1:5,000 dilution

Lysates/proteins at 10 µg per lane.

Predicted band size: 45 kDa

Observed band size: 45~50 kDa

Developed using the ECL technique (Cat. No. SQ201).

Product Name	Anti-Caspase 1 Mouse mAb
Description	Purified Recombinant Mouse Monoclonal Antibody
Application Applications Legend: WB=Western Blotting IHC-P=Immunohistochemistry (Paraffin) IHC-F=Immunohistochemistry (Frozen) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, ELISA
Dilution	WB 1:1,000~1:2,000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Clone No.	88J80A65
Isotype	IgG
Label	Unconjugated
Immunogen	Recombinant protein corresponding to Human Caspase-1
Format	Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.

Synonyms	IL1BC; IL1BCE; CASP1; Caspase-1; CASP-1; Interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; p45; IL-1BC; ICE; IL-1 beta-converting enzyme.
Molecular weight	Calculated MW: 45 kDa; Observed MW: 45~50 kDa
Uniprot ID	P29466
Gene ID	834
Storage	Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
Precautions	Anti-Caspase 1 Mouse mAb [88J80A65] is for research use only and not for use in diagnostic or therapeutic procedures.

Background	This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012]

Background

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012]

Cellular Location	Cytoplasm. Cell membrane.

Tissue Location	Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain.

说明书下载

M016264 Anti-Caspase 1 Mouse mAb [88J80A65]

总篇数：加载中...

总影响因子：加载中...

最高影响因子：加载中...

加载中...

没有更多数据

产品中心

联系雅酶

上海市闵行区新骏环路760号1号楼3层

info@epizyme.cn

400-058-8030

技术支持(电话/微信)：

罗老师 15021027255

李老师 18301721288

黄老师 18217238522

如有任何关于雅酶产品问题
欢迎来信咨询

雅酶微信公众号

抗体

蛋白提取与定量

蛋白电泳

蛋白免疫印迹

蛋白表达纯化与分离

蛋白质

ELISA试剂盒

核酸相关实验

微生物培养

设备与耗材

细胞培养

网站首页