Purified Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M016258 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
| Product Name | Anti-XIAP Mouse mAb |
|---|---|
| Description | Purified Recombinant Mouse Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 83J34V71 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant full length protein corresponding to Human XIAP |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | AP 13 antibody; API3 antibody; Apoptosis Inhibitor 3 antibody; Baculoviral IAP repeat containing 4 antibody; Baculoviral IAP Repeat Containing Protein 4 antibody; Baculoviral IAP repeat-containing protein 4 antibody; BIRC 4 antibody; BIRC4 antibody; E3 ubiquitin-protein ligase XIAP antibody; hIAP-3 antibody; hIAP3 antibody; HILP antibody; IAP 3 antibody. |
|---|---|
| Molecular weight | Calculated MW: 57 kDa; Observed MW: 57 kDa |
| Uniprot ID | P98170 |
| Gene ID | 331 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-XIAP Mouse mAb [83J34V71] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011] |
|---|
| Cellular Location | Cytoplasm; Nucleus |
|---|
| Tissue Location | Expressed in colonic crypts (at protein level) (PubMed:30389919). Ubiquitous, except peripheral blood leukocytes (PubMed:8654366) |
|---|
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