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Anti-Smad3 Mouse mAb [58A72T10]

Purified Recombinant Mouse Monoclonal Antibody

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货号 规格 价格
M016251
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-Smad3 Mouse mAb [58A72T10]
Product NameAnti-Smad3 Mouse mAb
DescriptionPurified Recombinant Mouse Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
 WB, ELISA
DilutionWB 1:1,000~1:2,000
ReactivityHuman, Mouse, Rat
HostMouse
ClonalityMonoclonal
Clone No.58A72T10
IsotypeIgG
LabelUnconjugated
ImmunogenRecombinant full length protein corresponding to Human Smad3
FormatAffinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsMothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3; MADH3; SMAD3.
Molecular weightCalculated MW: 48 kDa; Observed MW: 48, 49 kDa
Uniprot ID P84022
Gene ID 4088
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-Smad3 Mouse mAb [58A72T10] is for research use only and not for use in diagnostic or therapeutic procedures.
Background The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by RefSeq, May 2022]
Cellular Location Cytoplasm; Nucleus

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