Purified Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M016232 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-Aurora A Mouse mAb [79D35C30]](https://cdn.epizyme.cn/uploads/products/202609/M016232-1.png?v=20260924155355)
| Product Name | Anti-Aurora A Mouse mAb |
|---|---|
| Description | Purified Recombinant Mouse Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 79D35C30 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein corresponding to Human AURKA |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | AURA; Aurka; Aurora 2; Aurora A; Aurora kinase A; Aurora-related kinase 1; Aurora/IPL1 like kinase; AURORA/IPL1-like kinase; Aurora/IPL1-related kinase 1; AURORA2; Breast tumor-amplified kinase; BTAK; hARK1; IAK. |
|---|---|
| Molecular weight | Calculated MW: 46 kDa; Observed MW: 46 kDa |
| Uniprot ID | O14965 |
| Gene ID | 6790 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Aurora A Mouse mAb [79D35C30] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
|---|
| Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Cytoplasm, cytoskeleton, spindle pole; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole; Cell projection, neuron projection; Cell projection, cilium; Cytoplasm, cytoskeleton, cilium basal body; Basolateral cell membrane. Note: localizes at the centrosome from early prophase until telophase, and to spindle pole MTs from prophase to anaphase; moves to the midbody during telophase and cytokinesis. |
|---|
| Tissue Location | Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. Induction: cell-cycle regulated, low in G1/S, accumulates during G2/M, and decreases rapidly after. |
|---|
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