Purified Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M016231 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-Cofilin/CFL1 Mouse mAb [32R49B99]](https://cdn.epizyme.cn/uploads/products/202609/M016231-1.png?v=20260924155354)
| Product Name | Anti-Cofilin/CFL1 Mouse mAb |
|---|---|
| Description | Purified Recombinant Mouse Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 32R49B99 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant full length protein corresponding to Human cofilin |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | 18 kDa phosphoprotein; CFL1; CFL; COF1_HUMAN; Cofilin 1; Cofilin 1 non muscle; Cofilin; Cofilin non muscle isoform; Cofilin-1; epididymis secretory protein Li 15; HEL-S-15; non-muscle isoform; p18. |
|---|---|
| Molecular weight | Calculated MW: 18 kDa; Observed MW: 19 kDa |
| Uniprot ID | P23528 |
| Gene ID | 1072 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Cofilin/CFL1 Mouse mAb [32R49B99] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004] |
|---|
| Cellular Location | Nucleus matrix; Cytoplasm, cytoskeleton; Cell projection, ruffle membrane (peripheral membrane protein); Cell projection, lamellipodium membrane (peripheral membrane protein); Cell projection, lamellipodium; Cell projection, growth cone; Cell projection, axon. Note: Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia; detected at the cleavage furrow and contractile ring during cytokinesis; almost completely in nucleus in cells exposed to heat shock or 10% DMSO. |
|---|
| Tissue Location | Widely distributed in various tissues. Induction: up-regulated in response to enterovirus 71 (EV71) infection (at protein level). (HPA: Low tissue specificity) |
|---|
总篇数：加载中...
总影响因子：加载中...
最高影响因子：加载中...
上海市闵行区新骏环路760号1号楼3层
400-058-8030
技术支持(电话/微信)：
罗老师 15021027255
李老师 18301721288
黄老师 18217238522
如有任何关于雅酶产品问题
欢迎来信咨询
雅酶微信公众号
Copyright © 2026上海雅酶生物医药科技有限公司（Epizyme Biotech）
沪ICP备2021002422号
