Purified Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M016227 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-Caveolin 1/CAV1 Mouse mAb [21T59N51]](https://cdn.epizyme.cn/uploads/products/202609/M016227-1.png?v=20260924155354)
| Product Name | Anti-Caveolin 1/CAV1 Mouse mAb |
|---|---|
| Description | Purified Recombinant Mouse Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 21T59N51 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein corresponding to Human Caveolin-1 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | CAV; CAV1; Caveolin-1. |
|---|---|
| Molecular weight | Calculated MW: 20 kDa; Observed MW: 17, 23 kDa |
| Uniprot ID | Q03135 |
| Gene ID | 857 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Caveolin 1/CAV1 Mouse mAb [21T59N51] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010] |
|---|
| Cellular Location | Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Golgi apparatus, trans-Golgi network (By similarity). Cytoplasm. Note: Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae. |
|---|
| Tissue Location | Skeletal muscle, liver, stomach, lung, kidney and heart (at protein level). Expressed in the brain. |
|---|
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