Purified Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M014932 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-IMPA1 Mouse mAb [52T65Q05]](https://files.epizyme.cn:5005/uploads/productimage/M014932-1.png)
![Anti-IMPA1 Mouse mAb [52T65Q05]](https://files.epizyme.cn:5005/uploads/productimage/M014932-2.png)
| Product Name | Anti-IMPA1 Mouse mAb |
|---|---|
| Description | Purified Recombinant Mouse Monoclonal Antibody |
Application
|
WB, IHC-P/IF (Tissue-P), ELISA |
| Dilution | WB 1:1,000~1:2,000; IHC-P 1:100~1:200; IF 1:100~1:200 |
| Reactivity | Human, Mouse (Cell) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 52T65Q05 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of human IMPA1 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | IMP 1, IMP, IMPA 1, IMPA, IMPA1, IMPA1_HUMAN, IMPase 1, IMPase, Inositol 1(or 4) monophosphatase, Inositol monophosphatase 1, Inositol monophosphatase, Inositol(myo) 1(or 4) monophosphatase 1, Inositol-1(or 4)-monophosphatase 1, Lithium sensitive myo inositol monophosphatase A1, Lithium-sensitive myo-inositol monophosphatase A1. |
|---|---|
| Molecular weight | Calculated MW: 30 kDa; Observed MW: 30 kDa |
| Uniprot ID | P29218 |
| Gene ID | 3612 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-IMPA1 Mouse mAb [52T65Q05] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13. [provided by RefSeq, Dec 2014]. |
|---|
| Cellular Location | Cytoplasm. |
|---|
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