Purified Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M013476 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-Lamin A/C Mouse mAb [50K77M13]](https://files.epizyme.cn:5005/uploads/antybody/M013476_1.jpg)
| Product Name | Anti-Lamin A/C Mouse mAb |
|---|---|
| Description | Purified Mouse Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:500~1:1,000 |
| Reactivity | Human, Mouse (Cell), Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 50K77M13 |
| Isotype | IgG2a |
| Label | Unconjugated |
| Immunogen | Purified recombinant human LMNA protein fragments expressed in E.coli. |
| Format | Buffer System: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Purification: Affinity Purified. |
| Synonyms | LMNA, LMN1, Prelamin-A/C. |
|---|---|
| Molecular weight | Calculated MW: 74 kDa; Observed MW: 74 kDa |
| Uniprot ID | P02545 |
| Gene ID | 4000 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Lamin A/C antibody [50K77M13] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Play an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence. |
|---|
总篇数：加载中...
总影响因子：加载中...
最高影响因子：加载中...
上海市闵行区新骏环路760号1号楼3层
400-058-8030
技术支持(电话/微信)：
张老师 18217238522
罗老师 15021027255
李老师 18301721288
如有任何关于雅酶产品问题
欢迎来信咨询
雅酶微信公众号
Copyright © 2023上海雅酶生物医药科技有限公司（Epizyme Biotech）
沪ICP备2021002422号
