Purified Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M013104 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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| Product Name | Anti-PI3 Kinase p85 alpha Mouse mAb |
|---|---|
| Description | Purified Mouse Monoclonal Antibody |
Application
|
WB, IHC-P/IF (Tissue-P), ELISA |
| Dilution | WB 1:500~1:1,000; IHC-P 1:50~1:100 |
| Reactivity | Human, Mouse (Cell), Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 31L18M14 |
| Isotype | IgG1 |
| Label | Unconjugated |
| Immunogen | Purified recombinant protein expressed in E.coli. |
| Format | Buffer System: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Purification: Affinity Purified. |
| Synonyms | PIK3R1, GRB1, Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha. |
|---|---|
| Molecular weight | Calculated MW: 84 kDa; Observed MW: 84 kDa |
| Uniprot ID | P27986 |
| Gene ID | 5295 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-PI3 Kinase p85 alpha antibody [31L18M14] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. |
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