Purified Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M012702 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-HP1 alpha Mouse mAb [33L86L07]](https://files.epizyme.cn:5005/uploads/products/202601/M012702-1.png)
| Product Name | Anti-HP1 alpha Mouse mAb |
|---|---|
| Description | Purified Recombinant Mouse Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 33L86L07 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of human HP1 alpha |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | HEL25; HP1; HP1A; HP1alpha; 2610029O15Rik; CBX5_HUMAN; CBX5; Antigen p25; Heterochromatin protein 1 homolog alpha (HP1 alpha); CBX5_MOUSE. |
|---|---|
| Molecular weight | Calculated MW: 22 kDa; Observed MW: 22 kDa |
| Uniprot ID | P45973 |
| Gene ID | 23468 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-HP1 alpha Mouse mAb [33L86L07] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
|---|
| Cellular Location | Nucleus Chromosome Chromosome Centromere Colocalizes with HNRNPU in the nucleus (PubMed:19617346). Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase (PubMed:19617346). Localizes to sites of DNA damage (PubMed:28977666). |
|---|
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