Purified Recombinant Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M012063 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-BRG1 Mouse mAb [67M06K27]](https://files.epizyme.cn:5005/uploads/products/202601/M012063-1.png)
| Product Name | Anti-BRG1 Mouse mAb |
|---|---|
| Description | Purified Recombinant Mouse Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 67M06K27 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of human BRG1 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | BAF190; BAF190A; BRG1; CSS4; MRD16; OTSC12; RTPS2; SNF2; SNF2-beta; SNF2L4; SNF2LB; SWI2; hSNF2b; HP1-BP72; SNF2beta; SW1/SNF; b2b508.1Clo; b2b692Clo; brg-1; SMCA4_HUMAN; SMARCA4; BRG1-associated factor 190A (BAF190A); Mitotic growth and transcription activator; Protein BRG-1; Protein brahma homolog 1; Transcription activator BRG1; 3.6.4.-; SNF2B; SMCA4_MOUSE; SMCA4_RAT. |
|---|---|
| Molecular weight | Calculated MW: 185 kDa; Observed MW: 185 kDa |
| Uniprot ID | P51532 |
| Gene ID | 6597 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-BRG1 Mouse mAb [67M06K27] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] |
|---|
| Cellular Location | Nucleus Colocalizes with long non-coding RNA Evf2 in nuclear RNA clouds (By similarity). Localizes to sites of DNA damage (PubMed:25593309). |
|---|
| Tissue Location | Colocalizes with ZEB1 in E-cadherin-negative cells from established lines, and stroma of normal colon as well as in de-differentiated epithelial cells at the invasion front of colorectal carcinomas (at protein level). |
|---|
总篇数：加载中...
总影响因子：加载中...
最高影响因子：加载中...
上海市闵行区新骏环路760号1号楼3层
400-058-8030
技术支持(电话/微信)：
张老师 18217238522
罗老师 15021027255
李老师 18301721288
如有任何关于雅酶产品问题
欢迎来信咨询
雅酶微信公众号
Copyright © 2023上海雅酶生物医药科技有限公司（Epizyme Biotech）
沪ICP备2021002422号
