Purified Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M012020 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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| Product Name | Anti-DNA PKcs Mouse mAb |
|---|---|
| Description | Purified Mouse Monoclonal Antibody |
Application
|
IP, ELISA, WB, ICC/IF (Cell) |
| Dilution | WB 1:500~1:1,000; IF 1:50~1:200; IP 1:20 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 59L32M29 |
| Isotype | IgG2b |
| Label | Unconjugated |
| Immunogen | Purified recombinant human DNA-PKcs protein fragments expressed in E.coli |
| Format | Buffer System: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Purification: Affinity Purified. |
| Synonyms | PRKDC, HYRC, HYRC1, DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, DNA-PKcs, DNPK1, p460. |
|---|---|
| Molecular weight | Calculated MW: 469 kDa; Observed MW: 450 kDa |
| Uniprot ID | P78527 |
| Gene ID | 5591 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-DNA PKcs antibody [59L32M29] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties. |
|---|
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