Purified Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M011550 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-CD45 Mouse mAb [85L19L06]](https://cdn.epizyme.cn/uploads/antybody/M011550_1.jpg?v=20231201113124)
![Anti-CD45 Mouse mAb [85L19L06]](https://cdn.epizyme.cn/uploads/antybody/M011550_2.jpg?v=20231201113124)
![Anti-CD45 Mouse mAb [85L19L06]](https://cdn.epizyme.cn/uploads/antybody/M011550_3.jpg?v=20231201113124)
| Product Name | Anti-CD45 Mouse mAb |
|---|---|
| Description | Purified Mouse Monoclonal Antibody |
Application
|
WB, IHC-P/IF (Tissue-P), ELISA |
| Dilution | WB 1:1,000~1:4,000; IHC-P 1:200~1:400 |
| Reactivity | Human, Mouse (Cell) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 85L19L06 |
| Isotype | IgG1 |
| Label | Unconjugated |
| Immunogen | Purified recombinant fragment of human PTPRC expressed in E. Coli. |
| Format | Buffer System: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Purification: Affinity Purified. |
| Synonyms | PTPRC, CD45, Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, L-CA, T200, CD antigen CD45. |
|---|---|
| Molecular weight | Calculated MW: 147 kDa; Observed MW: 180-240kDa |
| Uniprot ID | P08575 |
| Gene ID | 5788 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-CD45 antibody [85L19L06] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. |
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