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Anti-Phospho-AKT (Ser473) Mouse mAb [45L37L61]

Purified Mouse Monoclonal Antibody

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货号 规格 价格
M011364
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-Phospho-AKT (Ser473) Mouse mAb [45L37L61]
Anti-Phospho-AKT (Ser473) Mouse mAb [45L37L61]
Product NameAnti-Phospho-AKT (Ser473) Mouse mAb
DescriptionPurified Mouse Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P/IF (Tissue-P), ELISA
DilutionWB 1:500~1:1,000; IHC-P 1:50~1:100
ReactivityHuman
HostMouse
ClonalityMonoclonal
Clone No.45L37L61
IsotypeIgG1
LabelUnconjugated
ImmunogenSynthetic peptide conjugated to KLH.
FormatBuffer System: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Purification: Affinity Purified.
SynonymsAKT1, PKB, RAC, RAC-alpha serine/threonine-protein kinase, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha.
Molecular weightCalculated MW: 56 kDa; Observed MW: 60 kDa
Uniprot ID P31749
Gene ID 207
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-Phospho-AKT (Ser473) antibody [45L37L61] is for research use only and not for use in diagnostic or therapeutic procedures.
Background Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.

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