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Anti-beta Arrestin 1 Mouse mAb [15M67L12]

Purified Mouse Monoclonal Antibody

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货号 规格 价格
M011168
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-beta Arrestin 1 Mouse mAb [15M67L12]
Product NameAnti-beta Arrestin 1 Mouse mAb
DescriptionPurified Mouse Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:500~1:1,000
ReactivityHuman
HostMouse
ClonalityMonoclonal
Clone No.15M67L12
IsotypeIgG2b
LabelUnconjugated
ImmunogenRecombinant human β-Arrestin 1 protein.
FormatBuffer System: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Purification: Affinity Purified.
SynonymsARB1, ARR1, ARRB1, ARRB1_HUMAN, Arrestin 2, Arrestin beta 1, Arrestin beta-1, Beta-arrestin-1.
Molecular weightCalculated MW: 47 kDa; Observed MW: 51 kDa
Uniprot ID P49407
Gene ID 408
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-beta Arrestin 1 antibody [15M67L12] is for research use only and not for use in diagnostic or therapeutic procedures.
Background Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]

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