Purified Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M011088 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-eIF4E Mouse mAb [14K08L25]](https://files.epizyme.cn:5005/uploads/antybody/M011088_1.jpg)
![Anti-eIF4E Mouse mAb [14K08L25]](https://files.epizyme.cn:5005/uploads/antybody/M011088_2.jpg)
| Product Name | Anti-eIF4E Mouse mAb |
|---|---|
| Description | Purified Mouse Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:500~1:1,000 |
| Reactivity | Human, Mouse (Cell), Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 14K08L25 |
| Isotype | IgG1 |
| Label | Unconjugated |
| Immunogen | Purified recombinant human eif4e protein expressed in E.coli. |
| Format | Buffer System: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Purification: Affinity Purified. |
| Synonyms | EIF4E, EIF4EL1, EIF4F, Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein. |
|---|---|
| Molecular weight | Calculated MW: 25 kDa; Observed MW: 25 kDa |
| Uniprot ID | P06730 |
| Gene ID | 1977 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-eIF4E antibody [14K08L25] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. |
|---|
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