Purified Mouse Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| M010825 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-BRAF Mouse mAb [29M43L94]](https://files.epizyme.cn:5005/uploads/antybody/M010825_1.jpg)
| Product Name | Anti-BRAF Mouse mAb |
|---|---|
| Description | Purified Mouse Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:500~1:1,000 |
| Reactivity | Mouse (Cell), Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 29M43L94 |
| Isotype | IgG2a |
| Label | Unconjugated |
| Immunogen | Purified recombinant human B Raf protein fragments expressed in E.coli. |
| Format | Buffer System: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Purification: Affinity Purified. |
| Synonyms | BRAF, BRAF1, RAFB1, Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1. |
|---|---|
| Molecular weight | Calculated MW: 84 kDa; Observed MW: 87 kDa |
| Uniprot ID | P15056 |
| Gene ID | 673 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-BRAF antibody [29M43L94] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Frequently mutated in thyroid cancers, skin melanomas and at lower frequency in a wide range of human cancers. An activating mutation, mimicking phosphorylation of the activation loop, is seen in 60% of malignant melanoma samples. Raf mutations are generally exclusive to Ras activating mutations. |
|---|
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